• Medientyp: E-Artikel
  • Titel: Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment
  • Beteiligte: Wiechert, Lars [VerfasserIn]; Heß, Jochen [VerfasserIn]
  • Erschienen: 2012
  • Erschienen in: Cell communication and signaling ; 10(2012), Seite 40
  • Sprache: Englisch
  • DOI: 10.1186/1478-811X-10-40
  • Identifikator:
  • Schlagwörter: Calgranulins ; Calprotectin ; Chemokines ; Hepatocytes ; Immune cell mobilization ; Neutrophils
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: Calprotectin consists of the Ca2+-binding proteins S100a8 and S100a9 that are induced in epithelial cells in response to tissue damage and infection. Both proteins are also secreted by activated innate immune cells and numerous studies demonstrate their crucial role in pathological conditions of acute and chronic inflammation.
  • Zugangsstatus: Freier Zugang