Prognostische Bedeutung seltener Einzelchromosomenanomalien bei myelodysplastischen Syndromen
= Prognostic impact of rare single chromosomatic anomalities at myelodysplastic syndroms
Beschreibung:
Cytogenetic in myelodysplastic syndromes offer a valid prognostic factor for OS and AML free survival in the IPSS-R. For roughly 90% of cytogenetic abnormalities the prognostic impact is already known. This analysis therefore deals with some of these rare single abnormalities within the remaining 10%. More than 7000 cases where screened. Core results refer to the del(13q) and balanced translocations with a significantly better survival rate and to abnormalities at chromosomes 20 (without del (20q)) and patients with monosomie 9 which have a significantly shorter overall survival rate. For m...