• Medientyp: E-Book
  • Titel: Theoretical Aspects of Population Genetics. (MPB-4), Volume 4
  • Beteiligte: Kimura, Motoo [Verfasser:in]; Ohta, Tomoko [Verfasser:in]
  • Erschienen: Princeton, NJ: Princeton University Press, [2020]
    [Online-Ausgabe]
  • Erschienen in: Monographs in Population Biology ; 114
  • Umfang: 1 Online-Ressource (1 online resource)
  • Sprache: Englisch
  • DOI: 10.12987/9780691210094
  • ISBN: 9780691210094
  • Identifikator:
  • Schlagwörter: Population genetics Mathematical models ; SCIENCE / Life Sciences / Genetics & Genomics ; F-statistics ; G-C content ; K distribution ; Malthusian parameter ; Ordovician ; adaptive surface ; apparent ; breeding structure ; chromosomal variation ; darwin ; evolutionary rates ; fossils, living ; insulins ; lethal equivalent ; linkage disequilibrium ; mutation, advantageous ; natural selection ; quasi-equilibrium surface ; rate of ; selection ; selective values ; steady flux equation ;
  • Art der Reproduktion: [Online-Ausgabe]
  • Entstehung:
  • Anmerkungen: In English
    Mode of access: Internet via World Wide Web
  • Beschreibung: Frontmatter -- Preface -- Contents -- CHAPTER ONE. Fate of an Individual Mutant Gene in a Finite Population -- CHAPTER TWO. Population Genetics and Molecular Evolution -- CHAPTER THREE. Effective Population Number -- CHAPTER FOUR. Natural Selection and Genetic Loads -- CHAPTER FIVE. Adaptive Evolution and Substitutional Load -- CHAPTER SIX. Two-locus Problems -- CHAPTER SEVEN. Linkage Disequilibrium and Associative Overdominance in a Finite Population -- CHAPTER EIGHT. Breeding Structure of Populations -- CHAPTER NINE. Maintenance of Genetic Variability In Mendelian Populations -- CHAPTER TEN. The Role of Sexual Reproduction in Evolution -- Mathematical Appendix -- Bibliography -- Author Index -- Subject Index

    To show the importance of stochastic processes in the change of gene frequencies, the authors discuss topics ranging from molecular evolution to two-locus problems in terms of diffusion models. Throughout their discussion, they come to grips with one of the most challenging problems in population genetics--the ways in which genetic variability is maintained in Mendelian populations.R.A. Fisher, J.B.S. Haldane, and Sewall Wright, in pioneering works, confirmed the usefulness of mathematical theory in population genetics. The synthesis their work achieved is recognized today as mathematical genetics, that branch of genetics whose aim is to investigate the laws governing the genetic structure of natural populations and, consequently, to clarify the mechanisms of evolution.For the benefit of population geneticists without advanced mathematical training, Professors Kimura and Ohta use verbal description rather than mathematical symbolism wherever practicable. A mathematical appendix is included
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