• Medientyp: E-Book; Hochschulschrift
  • Titel: Imaging network alterations in patients with genetic generalized epilepsy and their healthy Siblings using magneto- and electroencephalography
  • Beteiligte: Stier, Christina [VerfasserIn]; Focke, Niels [AkademischeR BetreuerIn]; Gail, Alexander [AkademischeR BetreuerIn]
  • Erschienen: Göttingen, 2022
  • Umfang: 1 Online-Ressource; Illustrationen, Diagramme
  • Sprache: Englisch
  • Identifikator:
  • Schlagwörter: MEG ; EEG ; MRI ; resting-state ; functional connectivity ; imaging endophenotypes ; network analysis ; epilepsy ; lifespan ; cortical thickness ; Hochschulschrift
  • Entstehung:
  • Hochschulschrift: Dissertation, Georg-August-Universität Göttingen, 2022
  • Anmerkungen:
  • Beschreibung: Genetic generalized epilepsy (GGE) is a common epilepsy syndrome and represents the largest group of epilepsies suspected to have a complex genetic etiology. Specific time windows for age of onset and various seizure types that rapidly engage bilateral networks of the brain characterize GGE. Another hallmark of GGE is the occurrence of brief, transient synchronized discharges in the 2-3 Hz range, as observed in the electroencephalogram. To date, there is no clear understanding of how large-scale brain networks behave in the absence of seizures or discharges, that is, during the interictal s...
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