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Zhang, Siyu [Verfasser:in]; Xie, Yanqiao [Verfasser:in]; Song, Leixin [Verfasser:in]; Wang, Yu [Verfasser:in]; Qiu, Hao [Verfasser:in]; Yang, Yingbo [Verfasser:in]; Li, Chunge [Verfasser:in]; Wang, Zhengtao [Verfasser:in]; Han, Zhuzhen [Verfasser:in]; Yang, Li [Verfasser:in]

Seven New 2-(2-Phenylethyl) Chromone Derivatives from Agarwood of Aquilaria Agallocha with Inhibitory Effects on Nitric Oxide Production

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  • Medientyp: E-Book
  • Titel: Seven New 2-(2-Phenylethyl) Chromone Derivatives from Agarwood of Aquilaria Agallocha with Inhibitory Effects on Nitric Oxide Production
  • Beteiligte: Zhang, Siyu [Verfasser:in]; Xie, Yanqiao [Verfasser:in]; Song, Leixin [Verfasser:in]; Wang, Yu [Verfasser:in]; Qiu, Hao [Verfasser:in]; Yang, Yingbo [Verfasser:in]; Li, Chunge [Verfasser:in]; Wang, Zhengtao [Verfasser:in]; Han, Zhuzhen [Verfasser:in]; Yang, Li [Verfasser:in]
  • Erschienen: [S.l.]: SSRN, [2022]
  • Umfang: 1 Online-Ressource (17 p)
  • Sprache: Englisch
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: Seven new 2-(2-Phenethyl) chromone derivatives ( 1-7 ), including four 2-(2-Phenethyl) chromone s ( 1-4 ), one 6, 7, 8 trihydroxy-2-(2-Phenethyl) chromone ( 5 ), one acetylated 5, 6, 7, 8-tetrahydroxy-2-(2-Phenethyl) chromone ( 6 ), and one chlorine-containing 5, 6, 7, 8-tetrahydro-2-(2-Phenethyl) chromone ( 7 ), along with eight known compounds ( 8-15 ), were isolated from agarwood originating from Aquilaria agallocha Roxb.. Their structures were determined mainly by high-resolution electrospray ionization mass spectrometry (HR-ESI-MS) and nuclear magnetic resonance (NMR) analysis. The absolute configurations of 3 - 7 were resolved by electronic circular dichroism (ECD) calculations. Nearly all compounds were evaluated for their anti-inflammatory activities in RAW264.7 cells. Compounds 1 and 7-11 displayed significant anti-inflammatory activities with IC 50 values ranging from 3.71 to 32.04 μM
  • Zugangsstatus: Freier Zugang