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Medientyp:
E-Book;
Hochschulschrift
Titel:
Konfokale Mikroskopie zur Detektion von Schäden an den Nervenfasern der Kornea bei chronischer inflammatorischer demyelinisierender Polyneuropathie
Paralleltitel:
Confocal Microscopy for Detection of Corneal Nerve Damages in Chronic Inflammatory Demyelinating Polyneuropathy
Beschreibung:
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoinflammatory disease of the peripheral nerve system typically leading to weakness and sensory symptoms. Moreover, small fiber neuropathy associated with dysesthesia and neuropathic pain regularly occurs in CIDP. So far, validated biomarkers longitudinally evaluating the impairment of small fibers to potentially assess disease progression and therapy effects are lacking. Corneal confocal microscopy (CCM) non-invasively examines the subbasal nerve plexus of the cornea consisting of Aδ and C fibers of trigeminal nerve branches....