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Stein, Thomas [VerfasserIn]; Taron, Jana [VerfasserIn]; Verloh, Niklas [VerfasserIn]; Doppler, Michael [VerfasserIn]; Rau, Alexander [VerfasserIn]; Hagar, Muhammad Taha [VerfasserIn]; Faby, Sebastian [VerfasserIn]; Baltas, Dimos [VerfasserIn]; Westermann, Dirk [VerfasserIn]; Ayx, Isabelle [VerfasserIn]; Schönberg, Stefan [VerfasserIn]; Nikolaou, Konstantin [VerfasserIn]; Schlett, Christopher L. [VerfasserIn]; Bamberg, Fabian [VerfasserIn]; Weiss, Jakob [VerfasserIn]

Photon-counting computed tomography of coronary and peripheral artery stents : a phantom study

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  • Medientyp: E-Artikel
  • Titel: Photon-counting computed tomography of coronary and peripheral artery stents : a phantom study
  • Beteiligte: Stein, Thomas [VerfasserIn]; Taron, Jana [VerfasserIn]; Verloh, Niklas [VerfasserIn]; Doppler, Michael [VerfasserIn]; Rau, Alexander [VerfasserIn]; Hagar, Muhammad Taha [VerfasserIn]; Faby, Sebastian [VerfasserIn]; Baltas, Dimos [VerfasserIn]; Westermann, Dirk [VerfasserIn]; Ayx, Isabelle [VerfasserIn]; Schönberg, Stefan [VerfasserIn]; Nikolaou, Konstantin [VerfasserIn]; Schlett, Christopher L. [VerfasserIn]; Bamberg, Fabian [VerfasserIn]; Weiss, Jakob [VerfasserIn]
  • Erschienen: 08 September 2023
  • Erschienen in: Scientific reports ; 13(2023), Artikel-ID 14806, Seite 1-11
  • Sprache: Englisch
  • DOI: 10.1038/s41598-023-41854-3
  • ISSN: 2045-2322
  • Identifikator:
  • Schlagwörter: Anatomy ; Cardiology ; Health care
  • Entstehung:
  • Anmerkungen: Online veröffentlicht: 08. September 2023
  • Beschreibung: Accurate small vessel stent visualization using CT remains challenging. Photon-counting CT (PCD-CT) may help to overcome this issue. We systematically investigate PCD-CT impact on small vessel stent assessment compared to energy-integrating-CT (EID). 12 water-contrast agent filled stents (3.0-8 mm) were scanned with patient-equivalent phantom using clinical PCD-CT and EID-CT. Images were reconstructed using dedicated vascular kernels. Subjective image quality was evaluated by 5 radiologists independently (5-point Likert-scale; 5 = excellent). Objective image quality was evaluated by calculating multi-row intensity profiles including edge rise slope (ERS) and coefficient-of-variation (CV). Highest overall reading scores were found for PCD-CT-Bv56 (3.6[3.3-4.3]). In pairwise comparison, differences were significant for PCD-CT-Bv56 vs. EID-CT-Bv40 (p ≤ 0.04), for sharpness and blooming respectively (all p < 0.05). Highest diagnostic confidence was found for PCD-CT-Bv56 (p ≤ 0.2). ANOVA revealed a significant effect of kernel strength on ERS (p < 0.001). CV decreased with stronger PCD-CT kernels, reaching its lowest in PCD-CT-Bv56 and highest in EID-CT reconstruction (p ≤ 0.05). We are the first study to verify, by phantom setup adapted to real patient settings, PCD-CT with a sharp vascular kernel provides the most favorable image quality for small vessel stent imaging. PCD-CT may reduce the number of invasive coronary angiograms, however, more studies needed to apply our results in clinical practice.
  • Zugangsstatus: Freier Zugang