Beschreibung:
Equipped with only three protons, lithium stands as one of the most unexpected drug discoveries in history. Despite its initial FDA approval in 1970, lithium's precise mechanism for regulating mood remains largely elusive. Lithium is generally considered a modulator of neurotransmission, an inhibitor of enzymes in the signaling cascade of inositol (1,4,5)-triphosphate and diacylglycerol, and neuroprotective. Yet, the true challenge lies in understanding how lithium effectively treats patients with bipolar disorder. Bipolar disorder is a psychiatric illness that is characterized by recurrent...