Low rate of function-limiting side effects with high-dose adjuvant radiotherapy in high-grade soft tissue extremity sarcomas: a retrospective single-center analysis over 10 years

Medientyp: E-Artikel
Titel: Low rate of function-limiting side effects with high-dose adjuvant radiotherapy in high-grade soft tissue extremity sarcomas : a retrospective single-center analysis over 10 years
Beteiligte: Köksal, Mümtaz [Verfasser:in]; van der Hoek, Maike [Verfasser:in]; Scafa, Davide [Verfasser:in]; Koch, David [Verfasser:in]; Leitzen, Christina [Verfasser:in]; Schmeel, Leonard C. [Verfasser:in]; Feldmann, Georg [Verfasser:in]; Strauss, Andreas [Verfasser:in]; Koob, Sebastian [Verfasser:in]; Giordano, Frank Anton [Verfasser:in]
Erschienen: July 2023
Erschienen in: Journal of cancer research and clinical oncology ; 149(2023), 8 vom: Juli, Seite 4877-4888
Sprache: Englisch
DOI: 10.1007/s00432-022-04423-1
Identifikator:

Schlagwörter: Adverse events ; Extremity sarcomas ; Local recurrences ; Radiotherapy ; Soft-tissue sarcomas
Entstehung:
Anmerkungen: Online veröffentlicht: 26. Oktober 2022
Beschreibung: Over the years, radiotherapy has been established as a tool to improve local control for high-grade sarcomas. Although the European Society for Medical Oncology guidelines has taken notice of a shift toward a neoadjuvant radiotherapy approach, the American Society for Radiation Oncology guidelines clearly favor a neoadjuvant approach, citing debilitating long-term adverse effects when radiotherapy is applied postoperatively. In this study, we examined these irradiation-associated adverse events for adjuvant radiotherapy and focused on the prognostic factors for disease outcome, including local control.
Zugangsstatus: Freier Zugang

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