Sejeroe-Olsen, B.
[Mitwirkende:r];
Shegunova, P.
[Mitwirkende:r];
Fromberg, A..
[Mitwirkende:r];
Held, A.
[Mitwirkende:r]
;
European Commission Joint Research Centre
Certification of the mass fraction of 3- and 2-MCPD fatty acid esters in infant formula
Beschreibung:
ERM-BD087 is an infant formula reference material certified for the mass fraction of the fatty acid esters of 3-chloro-1,2-propanediol (3-MCPD fatty acid ester also called bound 3-MCPD) and the sum of 3-chloro-1,2- propanediol (free 3-MCPD) and bound 3-MCPD, the fatty acid esters of 2-chloro-1,3-propanediol (2-MCPD fatty acid ester also called bound 2-MCPD) and the sum of 2-chloro-1,3-propanediol (free 2-MCPD) and bound 2-MCPD. Glycidyl fatty acid esters (GEs), are also present in the material. However, no mass fraction value was assigned to this compound due to indications of instability. ERM-BD087 is produced within the scope of ISO 17034:2016 [1] and in accordance with ISO Guide 35:2017 [2]. Infant formula containing 3-MCPD fatty acid esters, 2-MCPD fatty acid esters and glycidyl fatty acid esters was produced, using a contaminated coconut oil in the recipe. ERM-BD087 is available in glass vials containing at least 30 g of spray-dried infant formula powder, which were sealed under an atmosphere of nitrogen. Between-unit homogeneity was quantified and stability during transport and storage was assessed in accordance with ISO Guide 35:2017 [2]. The minimum sample size for one sample preparation is 0.4 g. The material was characterised by an inter-laboratory comparison of laboratories of demonstrated competence and adhering to ISO/IEC 17025:2017 [3]. Technically invalid results were removed but no outlier was eliminated since no technical reason for deviations was found. Uncertainties of the certified values were calculated in accordance with ISO 17034:2016 [1] and ISO Guide 35:2017 [2] and include uncertainties related to possible inhomogeneity, instability and characterisation. The material is intended for the quality control and assessment of method performance. Before release of the CRM, the certification project was subjected to peer-review involving both internal and external experts.