• Medientyp: Buch
  • Titel: Membrane protein structure and dynamics : methods and protocols
  • Enthält: Crystallization of membrane proteins in bicelles -- Vapor diffusion-controlled meso crystallization of membrane proteins -- Solution NMR studies of integral polytopic alpha-helical membrane proteins: The structure determination of the seven-helix transmembrane receptor sensory rhodopsin ii, psrii -- Use of NMR saturation transfer difference spectroscopy to study ligand binding to membrane proteins -- How to investigate interactions between membrane proteins and ligands by solid-state NMR -- Identifying and measuring transmembrane helix-helix interactions by FRET -- Studying substrate binding to reconstituted secondary transporters by attenuated total reflection infrared difference spectroscopy -- UV-visible and infrared methods for investigating lipid-rhodopsin membrane interactions -- Proteomic characterization of integral membrane proteins using thermostatted liquid chromatography coupled with tandem mass spectrometry -- LITiCon: A discrete conformational sampling computational method for mapping various functionally selective conformational states of transmembrane helical proteins -- Homology model-assisted elucidation of binding sites in GPCRs -- Comparative modeling of lipid receptors -- Quantification of structural distortions in the transmembrane helices of GPCRs -- Structure prediction of g protein-coupled receptors and their ensemble of functionally important conformations -- Target based virtual screening by docking into automatically generated GPCR models -- Predicting the biological activities through QSAR analysis and docking-based scoring -- Identification of motions in membrane proteins by elastic network models and their experimental validation -- Modeling the structural communication in supramolecular complexes involving GPCRs -- Exploring substrate diffusion in channels using biased molecular dynamics simulations.
  • Beteiligte: Vaidehi, Nagarajan [Hrsg.]
  • Erschienen: New York; Heidelberg [u.a.]: Humana Press, 2012
  • Erschienen in: Methods in molecular biology ; 914
    Springer protocols
  • Umfang: XI, 357 S.; Ill., graph. Darst
  • Sprache: Englisch
  • ISBN: 9781627030229
  • RVK-Notation: WE 5160 : Membranproteine allgemein
  • Schlagwörter: Membranproteine
  • Entstehung:
  • Anmerkungen: Literaturangaben
  • Weitere Bestandsnachweise
    0 : Methods in molecular biology

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  • Signatur: 2016 4 005521
  • Barcode: 11915641N