Sunnick, Eva Maria
[Verfasser:in]
;
Janshoff, Andreas
[Akademische:r Betreuer:in];
Janshoff, Andreas
[Sonstige Person, Familie und Körperschaft];
Rehfeldt, Florian
[Sonstige Person, Familie und Körperschaft]
Modell der Bildung und Stabilität von Adhäsionsclustern in biologischen Membranen
Beschreibung:
Cellular adhesion is pivotal in cell development, tissue formation and motility. The orchestration of cellular adhesion is an intricate process that involves a multitude of specialized proteins but at the same time follows a simple physical plan. Adhesion is based on non-covalent interactions predominantly between transmembrane proteins and the extracellular matrix. Most eukaryotic cells are able to create two-dimensional assemblies of integrins, so called focal adhesion clusters, which they use to stick to the substrate and collect information about the environmental properties. Integrins ...