Neumann, Gaby
[Verfasser:in]
;
Schäfer, Katrin
[Akademische:r Betreuer:in];
Schäfer, Katrin
[Sonstige Person, Familie und Körperschaft];
Schön, Margarete
[Sonstige Person, Familie und Körperschaft]
Die Überexpression der Integrin [beta]5-Untereinheit fördert die proangiogenetischen Fähigkeiten endothelialer Progenitorzellen
Beschreibung:
Angiogenesis is a hallmark of diverse physiological and pathological processes, including ischemia, inflammation, wound healing and tumor growth. The angiogenetic process depends on the proliferation, migration and morphogenesis of endothelial cells. In addition to local endothelial cells, endothelial progenitor cells (EPCs), mobilized from the bone marrow into the circulation in response to tissue injury have been shown to contribute to reendothelialization and neovascularisation. The vitronectin receptor integrin avß5 is expressed on endothelial progenitor cells and integrin activation ...