Rall, Nils Arne
[Verfasser:in]
;
Neumann, Heinz
[Akademische:r Betreuer:in];
Neumann, Heinz
[Sonstige Person, Familie und Körperschaft];
Urlaub, Henning
[Sonstige Person, Familie und Körperschaft]
A method for the quantitative analysis of protein-protein interactions in vivo
Beschreibung:
The function and activity of proteins is often modulated by other proteins they interact with. To understand cellular behaviour at the system level, a complete description of interactions among different proteins and the dynamic nature of these interactions is required. Identification and quantification of proteins based on measured peptide intensities represents the highest standard for an unbiased and definite determination of protein interaction partners. Inspired by the display of effectiveness of pBPA in vivo crosslinking in elucidating the mechanistic details of chromatin condensati...