• Medientyp: E-Book; Hochschulschrift
  • Titel: Physiology, metabolism and redox mechanisms in chronic cardiac volume overload
  • Beteiligte: Schnelle, Moritz Thomas [VerfasserIn]; Katschinski, Dörthe [AkademischeR BetreuerIn]; Katschinski, Dörthe [GutachterIn]; Shah, Ajay [GutachterIn]; Backs, Johannes [GutachterIn]
  • Erschienen: Göttingen, 2016
  • Umfang: 1 Online-Ressource; Illustrationen, Diagramme
  • Sprache: Englisch
  • Identifikator:
  • Schlagwörter: Hochschulschrift
  • Entstehung:
  • Hochschulschrift: Dissertation, Georg-August-Universität Göttingen, 2016
  • Anmerkungen:
  • Beschreibung: Chronic haemodynamic stress in the heart, induced by volume or pressure overload, contributes to cardiac dysfunction and heart failure and is associated with several human cardiovascular diseases (e.g. valvular heart diseases, arterial hypertension). Volume and pressure overload induce distinct cardiac remodelling responses in humans and mouse models, including different signalling patterns, but the differences between them are incompletely understood. In order to comprehensively study these, murine models of volume overload (aortocaval fistula, Shunt) and pressure overload (transverse aort...
  • Zugangsstatus: Freier Zugang