• Medientyp: Sonstige Veröffentlichung; E-Book; Bericht
  • Titel: Analysis of a tumor model as a multicomponent deformable porous medium
  • Beteiligte: Krejčí, Pavel [VerfasserIn]; Rocca, Elisabetta [VerfasserIn]; Sprekels, Jürgen [VerfasserIn]
  • Erschienen: Weierstrass Institute for Applied Analysis and Stochastics publication server, 2021
  • Sprache: Englisch
  • DOI: https://doi.org/10.20347/WIAS.PREPRINT.2842
  • Schlagwörter: 35Q92 ; 76S05 ; 35K57 ; 92B05 ; 35Q35 ; 92C37 ; article ; Tumor model -- porous medium -- diffuse interface model -- Cahn--Hilliard equation -- reaction-diffusion equation
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  • Beschreibung: We propose a diffuse interface model to describe tumor as a multicomponent deformable porous medium. We include mechanical effects in the model by coupling the mass balance equations for the tumor species and the nutrient dynamics to a mechanical equilibrium equation with phase-dependent elasticity coefficients. The resulting PDE system couples two Cahn--Hilliard type equations for the tumor phase and the healthy phase with a PDE linking the evolution of the interstitial fluid to the pressure of the system, a reaction-diffusion type equation for the nutrient proportion, and a quasistatic momentum balance. We prove here that the corresponding initial-boundary value problem has a solution in appropriate function spaces.
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