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Beschreibung:
Cancer is one of the major health problems in Europe and leads to enormous socioeconomic burdens. In 2019, 1.55 million people in the EU died from cancer, and 50\% of all cancer patients receive radiotherapy during the course of their disease. Microbeam radiation therapy is a promising approach to successfully minimize the damage to healthy tissue. Preclinical research with MST only became possible with the advent of large synchrotron facilities in the 1990s. However, these costly research facilities are unsuitable for widespread use in the healthcare system, leaving an unmet need for compact sources of microbeam therapy. The core of this work is the design and construction of a bearing and drive unit of a novel x-ray target for a compact microbeam source prototype. In addition to the historical development of x-ray sources, a principal design system is described in which the three bearing variants: rolling bearings, magnetic bearings and sliding bearings are compared on the basis of their technical characteristrics. The principle of a liquid metal lubricated plain bearing provided the best compromise with respect to the given requirements. For the design of the bearing system, the state of the art is analyzed based on a literature review. The relevant fundamentals for modeling the bearing, taking turbulence and cavitation into account, are presented. A recalculation and comparison with other models from the literature is carried out using numerical methods and an analytical solution of the pressure distribution. Based on this, the optimized parameters for the bearing of the rotating anode are calculated. In addition, the influences of frictional heat, manufacturing aspects of the bearing and corrosion due to the liquid metal are discussed and preventive measures are taken. With the bearing calculation completed, the design, construction and calculation of the drive train with target connection is carried out, which consists of two rotating rotor carriers running concentrically around a stationary axis. The ...