Stem cell and gene-based therapy: frontiers in regenerative medicine

Medientyp: E-Book

Titel: Stem cell and gene-based therapy : frontiers in regenerative medicine

Enthält: Preliminary; Renovation of the Injured Heart with Myocardial Tissue Engineering; Adult Stem Cells for Myocardial Tissue Repair; Regeneration of the Functional Myocardium Using Human Embryonic Stem Cells; Therapeutic Angiogenesis; Cell Therapy for Heart Failure; Cell Transplantation for Diseases of Myelin; Stem Cells as a Source for Cell Replacement in Parkinson's Disease; Cell Replacement Therapy in Acute Stroke: Current State; Gene Therapy to the Nervous System; Mesenchymal Stem Cells: Where Can You Find Them? How Can You Use Them?
Basic to Clinical Cartilage Engineering: Past, Present, and Future DiscussionsCartilage; Bone Regeneration; Osteoarthritis and Mesenchymal Cells - The Prospects for Repair of the Disease by Cell Transplantation and Tissue Engineering; Progenitor Cell Therapy for Kidney Regeneration; Tissue Engineering - The Bladder; Neuroprotection in Ophthalmology: A Review; Autoimmunity for Central Nervous System Maintenance, Regeneration, and Renewal: Development of a T Cell-Based Vaccination Against Neurodegeneration; Retinal Repair by Stem Cell Transplantation; Induction of Ocular Surface Regeneration
Insulin-Producing Cells Generated from Nonpancreatic TissuesGeneration of Islets from Pancreatic Progenitor Cells; Embryonic Stem Cells as a Source of Pancreatic Precursors and Islet Cells in Vitro; Human Umbilical Cord Blood Transplantation: A Viable Option for Stem Cell Graft; Nonmyeloablative Stem Cell Transplantation in the Treatment of Hematologic Malignancies; Hematopoietic Stem Cell Transplantation from Human Leukocyte Antigen Haploidentical Donor; Wound Healing and Skin Substitutes; Skin Regeneration from Multipotent Adult and Embryonic Stem Cells; Back matter
Section 1: Heart. Introduction / Alexander Battler and Jonathan Leor ; Renovation of the Injured Heart with Myocardial Tissue Engineering / Jonathan Leor, Natali Landa, and Smadar Cohen ; Adult Stem Cells for Myocardial Tissue Repair / Dirk Strunk and Christof Stamm ; Regeneration of the Functional Myocardium Using Human Embryonic Stem Cells / Oren Caspi and Lior Gepstien ; Therapeutic Angiogenesis / Shmuel Fuchs and Alexander Battler ; Cell Therapy for Heart Failure / Thorsten Reffelmann and Robert A. KlonerSection 2: Neuro. Introduction / Daniel Offen and Eldad Melamed ; Cell Transplantation for Diseases of Myelin / Tamir Ben-Hur and Ofira Einstein ; Stem Cells as a Source for Cell Replacement in Parkinson's Disease / Daniel Offen, Yossef S. Levy, and Eldad Melamed ; Cell Replacement Therapy in Acute Stroke: Current State / Yossi Gilgun-Sherki and Jonathan Y. Streifler ; Gene Therapy to the Nervous System / Hillel Haim and Israel Steiner -- Section 3: Musculoskeletal. Introduction / Zvi Nevo and Mark M. Levy ; Mesenchymal Stem Cells: Where Can You Find Them? How Can You Use Them? / Anna Derubeis, Giuseppina Pennesi, and Ranieri Cancedda ; Basic to Clinical Cartilage Engineering: Past, Present, and Future Discussions / Mats Brittberg, Tommi Tallheden, and Anders H. Lindahl ; Cartilage / Rocky S. Tuan and Faye H. Chen ; Bone Regeneration / A.H. Reddi ; Osteoarthritis and Mesenchymal Cells -- The Prospects for Repair of the Disease by Cell Transplantation and Tissue Engineering / Dror Robinson -- Secrion 4: Kidney. Introduction / Benjamin Dekel and Yair Reisner ; Progenitor Cell Therapy for Kidney Regeneration / Benjamin Dekel and Yair Reisner ; Tissue Engineering -- The Bladder / Anthony Atala -- Section 5: Eye. Introduction / Michael Belkin ; Neuroprotection in Ophthalmology: A Review / Yaniv Barkana and Michael Belkin ; Autoimmunity for Central Nervous System Maintenance, Regeneration, and Renewal: Development of a T Cell-Based Vaccination Against Neurodegeneration / Michal Schwartz and Jonathan Kipnis ; Retinal Repair by Stem Cell Transplantation / Jeffrey H. Stern, Sally Temple, and Soma De ; Induction of Ocular Surface Regeneration / Irina S. Barequet-- Section 6: Pancreas. Introduction / Shimon Efrat ; Insulin-Producing Cells Generated from Nonpancreatic Tissues / Shimon Efrat ; Generation of Islets from Pancreatic Progenitor Cells / Susan Bonner-Weir, Tandy Aye, Akari Inada, Elena Toschi, and Arun Sharma ; Embryonic Stem Cells as a Source of Pancreatic Precursors and Islet Cells In Vitro / Victoria L. Browning, Brenda W. Kahan, and Jon S. Odorico -- Section 7: Hematology. Introduction / Arnon Nagler ; Human Umbilical Cord Blood Transplantation: A Viable Option for Stem Cell Graft / Gal Goldstein, Amos Toren, and Arnon Nagler ; Nonmyeloablative Stem Cell Transplantation in the Treatment of Hematologic Malignancies / Avichai Shimoni and Arnon Nagler ; Hematopoietic Stem Cell Transplantation from Human Leukocyte Antigen Haploidentical Donor / Merav Leiba and Arnon Nagler -- Sectopn 8: Skin. Introduction / Nili Grossman ; Wound Healing and Skin Substitutes / Adam J. Singer and Marcia Simon ; Skin Regeneration from Multipotent Adult and Embryonic Stem Cells / Kursad Turksen and Tammy-Claire Troy.

Beteiligte: Battler, Alexander [HerausgeberIn]; Leor, Jonathan [HerausgeberIn]

Erschienen: London; Heidelberg; New York; Dordrecht: Springer, [2006]

Umfang: 1 Online-Ressource (xvii, 422 Seiten); Illustrationen, Diagramme

Sprache: Englisch

DOI: 10.1007/1-84628-142-3

ISBN: 9781846281426

Identifikator:

RVK-Notation: WG 7400 : Gentherapie

Schlagwörter: Gentherapie > Stammzelle
Stammzelle > Gentherapie

Entstehung:

Anmerkungen: Includes bibliographical references and index

Beschreibung: Regenerative medicine - stem cell and gene-based therapy - offers a new approach for restoring function of damaged organs and tissues. This is the first book to cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine.

The inability of the human body to be able significantly to self repair injured organs and tissues results in a considerable medical and social problem. During the last few years there has been incredible progress, and the achievements in experimental strategies for tissue regeneration, particularly in cell transplantation and stem cell research, have led to potential treatment options for many otherwise fatal conditions. These innovations hold promise for treating or preventing end-stage organ failure, cell therapy and tissue engineering of viable grafts with the potential to grow and remodel could provide prospective new solutions to the serious problems of organ donor shortage. Regenerative medicine - stem cell and gene-based therapy - offers a new approach for restoring function of damaged organs and tissues. Several books have been published on particular aspects of organ and/or tissue replacement but none cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine, allowing practitioners to gain knowledge not only of how regenerative medicine applies to their discipline directly but also how it could benefit their patients in the years to come.

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