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Schmidt, Andrej [Verfasser:in]; Schreve, Michiel A. [Verfasser:in]; Huizing, Eline [Verfasser:in]; Del Giudice, Constantino [Verfasser:in]; Branzan, Daniela [Verfasser:in]; Ünlü, Cagdas [Verfasser:in]; Varcoe, Ramon L. [Verfasser:in]; Ferraresi, Roberto [Verfasser:in]; Kum, Steven [Verfasser:in]

Midterm Outcomes of Percutaneous Deep Venous Arterialization With a Dedicated System for Patients With No-Option Chronic Limb-Threatening Ischemia

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  • Medientyp: E-Artikel
  • Titel: Midterm Outcomes of Percutaneous Deep Venous Arterialization With a Dedicated System for Patients With No-Option Chronic Limb-Threatening Ischemia : The ALPS Multicenter Study
  • Beteiligte: Schmidt, Andrej [Verfasser:in]; Schreve, Michiel A. [Verfasser:in]; Huizing, Eline [Verfasser:in]; Del Giudice, Constantino [Verfasser:in]; Branzan, Daniela [Verfasser:in]; Ünlü, Cagdas [Verfasser:in]; Varcoe, Ramon L. [Verfasser:in]; Ferraresi, Roberto [Verfasser:in]; Kum, Steven [Verfasser:in]
  • Erschienen: Thousand Oaks: SAGE Publications, [2023]
  • Erschienen in: Journal of Endovascular Therapy ; 27,4 (2020), Seite 658-665
  • Sprache: Englisch
  • Schlagwörter: below-the-knee arteries ; peripheral artery disease ; desert foot ; amputation ; endovascular technique ; limb salvage ; critical limb ischemia ; no-option CLTI ; infrapopliteal arteries ; chronic limb-threatening ischemia ; wound healing
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: Purpose: To evaluate the midterm results of patients suffering from no-option chronic limb-threatening ischemia (CLTI) treated with a dedicated system for percutaneous deep venous arterialization (pDVA). Materials and Methods: Thirty two consecutive CLTI patients (mean age 67±14 years; 20 men) treated with pDVA using the Limflow device at 4 centers between 11 July 2014 and 11 June 2018 were retrospectively analyzed. Of all patients, 21 (66%) had diabetes, 8 (25%) were on immunosuppression, 4 (16%) had dialysis-dependent renal failure, 9 (28%) had Rutherford category 6 ischemia, and 25 (78%) were deemed at high risk of amputation. The primary outcome was amputation-free survival (AFS) at 6 months. Secondary outcomes were wound healing, limb salvage, and survival at 6, 12, and 24 months. Results: Technical success was achieved in 31 patients (96.9%). The median follow-up was 34 months (range 16–63). At 6, 12, and 24 months, estimates were 83.9%, 71.0%, and 67.2% for AFS, 86.8%, 79.8% and 79.8% for limb salvage, and 36.6%, 68.2%, and 72.7% for complete wound healing, respectively. Median time to complete wound healing was 4.9 months (range 0.5–15). The DVA circuit occluded during follow-up in 21 patients; the median time to occlusion was 2.6 months. Reintervention for occlusion was performed in 17 patients: 16 because of unhealed wounds and 1 for a newly developed ulcer. Conclusion:This study represents the largest population of patients with no-option CLTI treated with pDVA using the LimFlow device with midterm results. In this complex group of patients, pDVA using the LimFlow device has been shown to be feasible, with a high technical success rate and AFS at 6 up to 24 months coupled with wound healing. In selected patients with no option CLTI, pDVA could be a recommended treatment to prevent amputation and heal wounds.
  • Zugangsstatus: Freier Zugang
  • Rechte-/Nutzungshinweise: Urheberrechtsschutz