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Surov, Alexey [Verfasser:in]; Akritidou, Mideia [Verfasser:in]; Bach, Andreas Gunther [Verfasser:in]; Bailis, Nikolaos [Verfasser:in]; Lerche, Marianne [Verfasser:in]; Meyer, Hans Jonas [Verfasser:in]; Pech, Maciej [Verfasser:in]; Wienke, Andreas [Verfasser:in]

A New Index for the Prediction of 30-Day Mortality in Patients With Pulmonary Embolism

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  • Medientyp: E-Artikel
  • Titel: A New Index for the Prediction of 30-Day Mortality in Patients With Pulmonary Embolism : The Pulmonary Embolism Mortality Score (PEMS)
  • Beteiligte: Surov, Alexey [Verfasser:in]; Akritidou, Mideia [Verfasser:in]; Bach, Andreas Gunther [Verfasser:in]; Bailis, Nikolaos [Verfasser:in]; Lerche, Marianne [Verfasser:in]; Meyer, Hans Jonas [Verfasser:in]; Pech, Maciej [Verfasser:in]; Wienke, Andreas [Verfasser:in]
  • Erschienen: Thousand Oaks: SAGE Publications, [2023]
  • Erschienen in: Angiology ; 72,8 (2021), Seite 787-793
  • Sprache: Englisch
  • Schlagwörter: simplified pulmonary embolism index ; acute pulmonary embolism ; computer tomographic pulmonary angiography ; 30-day mortality
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: Our aim was to analyze possibility of combination of basic clinical and radiological signs to predict 30-day mortality after acutepulmonary embolism (PE). We included 486 patients. Age, gender, simplified pulmonary embolism index (sPESI), pH, troponin,N-terminal natriuretic peptide, minimal systolic and diastolic blood pressure, O2 saturation, syncope, need for vasopressors,thrombotic obstruction, vessel diameter, short axis ratio right ventricle/left ventricle, and contrast medium reflux into the inferiorvena cava (IVC) were analyzed. A backward algorithm in a logistic regression model was used to identify relevant risk factors.Multiple logistic regression analysis identified that sPESI, pH, minimal diastolic blood pressure, IVC reflux, and need for vasopressors influenced 30-day mortality. A score for mortality prediction was constructed (the Pulmonary Embolism MortalityScore): sPESI >2 points (1 point), pH <7.35 (1 point), minimal diastolic blood pressure <45 mm Hg (1 point), IVC reflux (1 point),and need for vasopressors (2 points). Patients with >3 points showed higher 30-day mortality (sensitivity: 84.9%, specificity: 83.0%,positive predictive value: 51.8%, negative predictive value: 96.2%). The net reclassification improvement compared with the sPESIwas 0.94 (95% CI ¼ 0.73-1.15). In conclusion, a new score can predict 30-day mortality in patients with PE and is more sensitivethan sPESI
  • Zugangsstatus: Freier Zugang
  • Rechte-/Nutzungshinweise: Urheberrechtsschutz