Periodontal Inflamed Surface Area Is Associated With Increased Gestational Blood Pressure and Uric Acid Levels Among Pregnant Women From Rural North China
Sie können Bookmarks mittels Listen verwalten, loggen Sie sich dafür bitte in Ihr SLUB Benutzerkonto ein.
Medientyp:
E-Artikel
Titel:
Periodontal Inflamed Surface Area Is Associated With Increased Gestational Blood Pressure and Uric Acid Levels Among Pregnant Women From Rural North China
Beschreibung:
Background: Periodontal disease has been associated with gestational complicationsand both conditions have a high prevalence in rural populations from developing regions.A cross-sectional study was carried out to explore the relationship between periodontalinflamed surface area (PISA), blood pressure (BP), and, serum uric acid levels (UA) in agroup of rural North Chinese pregnant women in the third trimester of pregnancy.Methods: Three hundred and thirty-five rural women aged 20–34 years, with normalbody mass index (BMI) were examined in a cross-sectional study during their thirdtrimester of gestation. Exclusion criteria were history of pregnancy complications,multiplepregnancy, smoking habits, diabetes, hypertension or any known infectious disease.Socio-demographic variables, including age and socioeconomic status (SES), systolicblood pressure (SBP) and diastolic blood pressure (DBP) readings, serum UA levels,and PISA values were recorded. A structural equation model was implemented with twoconstructed latent variables including “Dem” (comprising of age and SES category torepresent unobserved demographic variables) and, “BP” (comprising of SBP and DBP toaccount for measurement error and lack of multiple BP readings). The model accountedfor co-variance of BP and UA, and implemented simultaneous regressions for BP andUA as outcomes, upon Dem and PISA values as exogenous variables.Results: The median PISA score was 1,081.7 (IQR = 835.01), reflecting high levels ofperiodontal inflammation in the sample. SEM showed a significant association of PISAwith BP (estimate = 0.011, 95%CI = 0.009–0.012 p < 0.001) and UA (estimate = 0.001,95% CI = 0.001–0.001, p < 0.001).Conclusion: Higher PISA values were significantly associated with higher bloodpressure and uric acid levels among rural pregnant women in a cross-sectional samplefrom a center in North China after accounting for a latent demographic construct derivedfrom age and SES.