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König, Sebastian [Verfasser:in]; Hohenstein, Sven [Verfasser:in]; Pellissier, Vincent [Verfasser:in]; Leiner, Johannes [Verfasser:in]; Hindricks, Gerhard [Verfasser:in]; Nachtigall, Irit [Verfasser:in]; Kuhlen, Ralf [Verfasser:in]; Bollmann, Andreas [Verfasser:in]

Changing trends of patient characteristics and treatment pathways during the COVID-19 pandemic

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  • Medientyp: E-Artikel
  • Titel: Changing trends of patient characteristics and treatment pathways during the COVID-19 pandemic : A cross-sectional analysis of 72,459 inpatient cases from the German Helios database
  • Beteiligte: König, Sebastian [Verfasser:in]; Hohenstein, Sven [Verfasser:in]; Pellissier, Vincent [Verfasser:in]; Leiner, Johannes [Verfasser:in]; Hindricks, Gerhard [Verfasser:in]; Nachtigall, Irit [Verfasser:in]; Kuhlen, Ralf [Verfasser:in]; Bollmann, Andreas [Verfasser:in]
  • Erschienen: Lausanne: Frontiers Media S.A., [2024]
  • Erschienen in: Frontiers in Public Health ; 10, (2022)
  • Sprache: Englisch
  • Schlagwörter: patient characteristics ; COVID-19 ; administrative data ; trend analysis ; in-hospitalmortality
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: Background: This study compared patient profiles and clinical courses ofSARS-CoV-2 infected inpatients over different pandemic periods.Methods: In a retrospective cross-sectional analysis, we examinedadministrative data of German Helios hospitals using ICD-10-codes atdischarge. Inpatient cases with SARS-CoV-2 infection admitted between03/04/2020 and 07/19/2022 were included irrespective of the reason forhospitalization. All endpoints were timely assigned to admission date for trendanalysis. The first pandemic wave was defined by change points in time-seriesof incident daily infections and compared with different later pandemic phasesaccording to virus type predominance.Results: We included 72,459 inpatient cases. Patients hospitalized during thefirst pandemic wave (03/04/2020–05/05/2020; n = 1,803) were older (68.5 ±17.2 vs. 64.4±22.6 years, p<0.01) and severe acute respiratory infections weremore prevalent (85.2 vs. 53.3%, p < 0.01). No differences were observed withrespect to distribution of sex, but comorbidity burden was higher in the firstpandemic wave. The risk of receiving intensive care therapy was reduced in alllater pandemic phases as was in-hospital mortality when compared to the firstpandemic wave. Trend analysis revealed declines of mean age and Elixhausercomorbidity index over time as well as a decline of the utilization of intensivecare therapy, mechanical ventilation and in-hospital mortality.Conclusion: Characteristics and outcomes of inpatients with SARS-CoV-2infection changed throughout the observational period. An ongoing evaluationof trends and care pathways will allow for the assessment of future demands
  • Zugangsstatus: Freier Zugang
  • Rechte-/Nutzungshinweise: Namensnennung (CC BY)