Beschreibung:
<jats:title>Abstract</jats:title><jats:p><jats:bold>Background</jats:bold> The incidence of strains of <jats:italic>Staphylococcus aureus</jats:italic> resistant to the antimicrobial agents used in treating impetigo has been increasing.</jats:p><jats:p><jats:bold>Aim</jats:bold> To determine the antimicrobial susceptibility of <jats:italic>S. aureus</jats:italic> in impetigo.</jats:p><jats:p><jats:bold>Methods</jats:bold> We measured the antimicrobial susceptibility of <jats:italic>Staphylococcus aureus</jats:italic> isolated from impetigo patients between 1994 and 2000.</jats:p><jats:p><jats:bold>Results</jats:bold> The MIC<jats:sub>50</jats:sub> of gentamicin was always higher than that of other antimicrobial agents until 1999. In isolates obtained since 1996, the MIC<jats:sub>90</jats:sub> of gentamicin was over 12.5 µg/mL, which is markedly higher than that found for other skin infections (folliculitis, furuncles, paronychia, phlegmone, secondary infection of eczema, dermatitis, ulcer and decubitus). There were no strains of <jats:italic>S. aureus</jats:italic> resistant to vancomycin and fusidic acid. After 2000, we could find only one strain resistant to minocycline and ofloxacin.</jats:p><jats:p><jats:bold>Conclusion</jats:bold> Clindamycin has shown excellent activity against most <jats:italic>S. aureus</jats:italic> isolates between 1994 and 2000. The incidence of methicillin‐resistant <jats:italic>S. aureus</jats:italic> was always below 20%.</jats:p>