• Medientyp: E-Artikel
  • Titel: Anthrax toxin rafts into cells
  • Beteiligte: Kurzchalia, Teymuras
  • Erschienen: Rockefeller University Press, 2003
  • Erschienen in: The Journal of Cell Biology
  • Sprache: Englisch
  • DOI: 10.1083/jcb.200301032
  • ISSN: 1540-8140; 0021-9525
  • Schlagwörter: Cell Biology
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p>Anthrax toxin binds to a plasma membrane receptor and after endocytosis exerts its deadly effects on the cell. Until now, however, the mechanism of initial toxin uptake was unknown. In this issue, Abrami et al. (2003) demonstrate that toxin oligomerization clusters the anthrax receptor into lipid rafts and this complex is internalized via the clathrin-dependent pathway.</jats:p>
  • Zugangsstatus: Freier Zugang