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Manion, Maura; Dimitrova, Dimana; Pei, Luxin; Gea-Banacloche, Juan; Zelazny, Adrian; Lisco, Andrea; Zerbe, Christa; Freeman, Alexandra F; Holland, Steven M; Kanakry, Christopher G; Kanakry, Jennifer A; Sereti, Irini

Immune Reconstitution Inflammatory Syndrome as a Posttransplantation Complication in Primary Immunodeficiency With Disseminated Mycobacterium avium

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  • Medientyp: E-Artikel
  • Titel: Immune Reconstitution Inflammatory Syndrome as a Posttransplantation Complication in Primary Immunodeficiency With Disseminated Mycobacterium avium
  • Beteiligte: Manion, Maura; Dimitrova, Dimana; Pei, Luxin; Gea-Banacloche, Juan; Zelazny, Adrian; Lisco, Andrea; Zerbe, Christa; Freeman, Alexandra F; Holland, Steven M; Kanakry, Christopher G; Kanakry, Jennifer A; Sereti, Irini
  • Erschienen: Oxford University Press (OUP), 2020
  • Erschienen in: Clinical Infectious Diseases
  • Sprache: Englisch
  • DOI: 10.1093/cid/ciz507
  • ISSN: 1058-4838; 1537-6591
  • Schlagwörter: Infectious Diseases ; Microbiology (medical)
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Abstract</jats:title> <jats:p>Patients with primary immunodeficiencies undergoing allogeneic hematopoietic cell transplantation (HCT) for difficult-to-control infections can experience immune reconstitution inflammatory syndrome (IRIS) following engraftment. In 3 patients with post-HCT IRIS related to mycobacterial infection, in vitro data demonstrate the emergence of pathogen-specific immune responses and a concomitant rise in plasma inflammatory markers.</jats:p>
  • Zugangsstatus: Freier Zugang