> Detailanzeige

Di Cori, Andrea; Auricchio, Angelo; Regoli, François; Blomström-Lundqvist, Carina; Butter, Christian; Dagres, Nikolaos; Deharo, Jean-Claude; Maggioni, Aldo P; Kutarski, Andrzej; Kennergren, Charles; Laroche, Cécile; Rinaldi, Christopher A; Dovellini, Emilio Vincenzo; Golzio, Pier Giorgio; Thøgersen, Anna Margrethe; Bongiorni, Maria Grazia

Clinical impact of antithrombotic therapy in transvenous lead extraction complications: a sub-analysis from the ESC-EORP EHRA ELECTRa (European Lead Extraction ConTRolled) Registry

Literatur-
verwaltung

Zur
Merkliste

Lösche von
Merkliste

Per Whatsapp teilen

Schließen

Merkliste



Sie können Bookmarks mittels Listen verwalten, loggen Sie sich dafür bitte in Ihr SLUB Benutzerkonto ein.
  • Medientyp: E-Artikel
  • Titel: Clinical impact of antithrombotic therapy in transvenous lead extraction complications: a sub-analysis from the ESC-EORP EHRA ELECTRa (European Lead Extraction ConTRolled) Registry
  • Beteiligte: Di Cori, Andrea; Auricchio, Angelo; Regoli, François; Blomström-Lundqvist, Carina; Butter, Christian; Dagres, Nikolaos; Deharo, Jean-Claude; Maggioni, Aldo P; Kutarski, Andrzej; Kennergren, Charles; Laroche, Cécile; Rinaldi, Christopher A; Dovellini, Emilio Vincenzo; Golzio, Pier Giorgio; Thøgersen, Anna Margrethe; Bongiorni, Maria Grazia
  • Erschienen: Oxford University Press (OUP), 2019
  • Erschienen in: EP Europace, 21 (2019) 7, Seite 1096-1105
  • Sprache: Englisch
  • DOI: 10.1093/europace/euz062
  • ISSN: 1099-5129; 1532-2092
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: Aims A sub-analysis of the ESC-EHRA European Lead Extraction ConTRolled (ELECTRa) Registry to evaluate the clinical impact of antithrombotic (AT) on transvenous lead extraction (TLE) safety and efficacy. Methods and results ELECTRa outcomes were compared between patients without AT therapy (No AT Group) and with different pre-operative AT regimens, including antiplatelets (AP), anticoagulants (AC), or both (AP + AC). Out of 3510 pts, 2398 (68%) were under AT pre-operatively. AT patients were older with more comorbidities (P < 0.0001). AT subgroups, defined as AP, AC, or AP + AC, were 1096 (31.2%), 985 (28%), and 317 (9%), respectively. Regarding AP patients, 1413 (40%) were under AP, 1292 (91%) with a single AP, interrupted in 26% about 3.8 ± 3.7 days before TLE. In total, 1302 (37%) patients were under AC, 881 vitamin K antagonist (68%), 221 (17%) direct oral anticoagulants, 155 (12%) low weight molecular heparin, and 45 (3.5%) unfractionated heparin. AC was ‘interrupted without bridging’ in 696 (54%) and ‘interrupted with bridging’ in 504 (39%) about 3.3 ± 2.3 days before TLE, and ‘continued’ in 87 (7%). TLE success rate was high in all subgroups. Only overall in-hospital death (1.4%), but not the procedure-related one, was higher in the AT subgroups (P = 0.0500). Age >65 years and New York Heart Association Class III/IV, but not AT regimens, were independent predictors of death for any cause. Haematomas were more frequent in AT subgroups, especially in AC ‘continued’ (P = 0.025), whereas pulmonary embolism in the No-AT (P < 0.01). Conclusions AT minimization is safe in patients undergoing TLE. AT does not seem to predict death but identifies a subset of fragile patients with a worse in-hospital TLE outcome.
  • Zugangsstatus: Freier Zugang