• Medientyp: E-Artikel
  • Titel: Viral Load Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Individuals With Coronavirus Disease 2019
  • Beteiligte: Regan, James; Flynn, James P; Rosenthal, Alexandra; Jordan, Hannah; Li, Yijia; Chishti, Rida; Giguel, Francoise; Corry, Heather; Coxen, Kendyll; Fajnzylber, Jesse; Gillespie, Elizabeth; Kuritzkes, Daniel R; Hacohen, Nir; Goldberg, Marcia B; Filbin, Michael R; Yu, Xu G; Baden, Lindsey; Ribeiro, Ruy M; Perelson, Alan S; Conway, Jessica M; Li, Jonathan Z; Abayneh, Betelihem A; Allen, Patrick; Alter, Galit; [...]
  • Erschienen: Oxford University Press (OUP), 2021
  • Erschienen in: Open Forum Infectious Diseases, 8 (2021) 8
  • Sprache: Englisch
  • DOI: 10.1093/ofid/ofab153
  • ISSN: 2328-8957
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) kinetics remain understudied, including the impact of remdesivir. In hospitalized individuals, peak sputum viral load occurred in week 2 of symptoms, whereas viremia peaked within 1 week of symptom-onset, suggesting early systemic seeding of SARS-CoV-2. Remdesivir treatment was associated with faster viral decay.
  • Zugangsstatus: Freier Zugang