• Medientyp: E-Artikel
  • Titel: Muscle protein synthesis is suboptimal following a typical carbohydrate‐rich breakfast
  • Beteiligte: Mamerow, Madonna Marie; Mettler, Joni A.; English, Kirk L.; Layman, Donald K.; Volpi, Elena; Paddon-Jones, Douglas
  • Erschienen: Wiley, 2012
  • Erschienen in: The FASEB Journal
  • Sprache: Englisch
  • DOI: 10.1096/fasebj.26.1_supplement.1013.7
  • ISSN: 1530-6860; 0892-6638
  • Schlagwörter: Genetics ; Molecular Biology ; Biochemistry ; Biotechnology
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  • Beschreibung: <jats:p>Most Americans generally consume a relatively small amount of dietary protein at breakfast, typically less than 10 grams, and favor carbohydrate‐rich breakfasts. Yet, some evidence suggests that approximately 25–30 g protein is needed to maximally stimulate muscle protein synthesis rates. The objective of this study examined the acute and sustained effects of a 30 g protein‐rich breakfast meal compared to the typical 10 g American breakfast. Healthy adult men and women (n=11, 38+/−2.98 y, BMI: 26.1+/− 1.1) participated in a 7‐day crossover feeding study with 30 day washout. Study diets were isoenergetic, with Diet 1 providing 30 g protein at each breakfast meal and Diet 2 providing 10 g. Stable isotope methodology with muscle biopsies and blood sampling was used to assess muscle protein synthesis. Day 1 results indicated that the 30 g protein breakfast enhanced muscle fractional synthesis rates to a greater extent than the 10 g protein breakfast and was sustained throughout day 7. In conclusion, compared to the typical carbohydrate‐rich American breakfast, consuming a moderate amount of protein (30 g) at breakfast may promote increased utilization of dietary protein and enhanced muscle synthesis in adults.</jats:p>