Beschreibung:
<jats:p>Exercise variably increases high density lipoprotein, HDL, cholesterol; little information is available for effects on density distributions that may better reflect HDL functionality. 45 normolipidemic, untrained subjects completed one of four exercise modalities that progressively increased energy expenditure over a 8wk period without diet change. From wk 8‐12 exercise intensity was constant and created a 500 kcal/wk expenditure for each modality. Density distributions were determined by imaging fluorescently stained plasma lipoproteins follow isopycnic separation before and at the end of the 12 wk training period. Body fat was determined by DEXA and averaged 40.2% at week 0 and 38.4% at week 12 (p<0.05); relative VO2 max mL O2/min/kg body weight increased 13% from 30.0 to 33.9 over this same time interval (p < 0.05). Total lipoprotein area under the curve did not change with exercise. No lipoprotein subfraction was found to be associated with relative VO2 max in untrained individuals. At week 12, regardless of exercise group, relative VO2 max was negatively correlated (p<0.05) with HDL3b, low‐density lipoprotein subfraction 2, LDL2, and LDL3. These findings show that increasing VO2 max, independent of exercise modality and diet modification, can have positive impact on lipoprotein profiles in the absence of changes in plasma cholesterol or HDL‐C.</jats:p>