• Medientyp: E-Artikel
  • Titel: Evaluation of a New Material From an Allogenic Collagen Scaffold as a Suitable Coupling Option for Round Window Vibroplasty
  • Beteiligte: Wolber, Philipp; Stürmer, Konrad; Pazen, David; Cimen, Tim; Klußmann, Jens Peter; Lüers, Jan-Christoffer; Schwarz, David
  • Erschienen: Ovid Technologies (Wolters Kluwer Health), 2021
  • Erschienen in: Otology & Neurotology
  • Sprache: Englisch
  • DOI: 10.1097/mao.0000000000002961
  • ISSN: 1531-7129; 1537-4505
  • Schlagwörter: Neurology (clinical) ; Sensory Systems ; Otorhinolaryngology
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  • Beschreibung: <jats:sec> <jats:title>Introduction:</jats:title> <jats:p>In round window vibroplasty the most efficient coupling technique for contact of the floating mass transducer (FMT) to the round window membrane (RWM) is yet to be determined. Various materials placed between the FMT and the RWM have been proposed to enable better stimulation of the cochlea. Collagenous scaffolds derived from decellularized extracellular cartilage matrices as a commercially available biomaterial are already used for other applications in ear surgery. We aimed to examine the coupling properties of collagen scaffolds compared with commonly used other materials (round window soft coupler, porcine perichondrium, and cartilage) as interponate between the FMT and the RWM in vibroplasty.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods:</jats:title> <jats:p>A well-established in vitro temporal bone model was used. Volume velocities were measured with collagen scaffold compared with different interponates (round window soft coupler, porcine perichondrium, and cartilage) at 800, 1000, 1250, 1600, 2000, 2500, 3150, and 4000 Hz levels.</jats:p> </jats:sec> <jats:sec> <jats:title>Results:</jats:title> <jats:p>Statistical analysis revealed no superiority of commonly used materials compared with collagen scaffolds at all tested volume velocities (<jats:italic toggle="yes">p</jats:italic> &gt; 0.05).</jats:p> </jats:sec> <jats:sec> <jats:title>Discussion:</jats:title> <jats:p>We could demonstrate that collagenous scaffolds of decellularized extracellular cartilage matrices have similar vibrational properties as conventional coupling materials of the FMT to the RWM in vibroplasty. Therefore, as a commercially available new material they display a suitable coupling option for round window vibroplasty.</jats:p> </jats:sec>