Beschreibung:
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<jats:title>Introduction:</jats:title>
<jats:p>Isolated splenic metastasis emanating from colorectal cancer is an extremely rare finding, which usually indicates widely disseminated and multiple metastatic cancer. There have only been 39 cases of isolated splenic metastasis reported in the English literature to date.</jats:p>
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<jats:title>Patient concerns:</jats:title>
<jats:p>An 84-year-old female patient presented to our department with dark-red bloody stool that had persisted for 1 month and with an increased serum carcinoembryonic antigen (CEA) level.</jats:p>
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<jats:title>Diagnoses:</jats:title>
<jats:p>A colonoscopy showed a rectal mass located 3 cm from the anal margin, which was 45 mm in diameter. The patient was diagnosed with rectal cancer with splenic metastases by abdomen computed tomography.</jats:p>
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<jats:title>Interventions:</jats:title>
<jats:p>The patient underwent a radical resection of rectal cancer and splenectomy, and the postoperative histopathology confirmed that the splenic lesions were derived from the adenocarcinoma of the rectum.</jats:p>
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<jats:title>Outcomes:</jats:title>
<jats:p>After surgical treatment, the patient recovered well and was recommended for further chemotherapy.</jats:p>
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<jats:title>Conclusions:</jats:title>
<jats:p>In addition to revealing a rare case, we also performed a literature review, including a brief discussion about the atypical isolated splenic metastasis from colorectal cancer. Our findings enrich the database of this rare clinical entity and provide experience in the management of splenic metastasis.</jats:p>
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