• Medientyp: E-Artikel
  • Titel: 68Ga-PSMA PET/MR–Positive, Histopathology-Proven Prostate Cancer in a Patient With Negative Multiparametric Prostate MRI
  • Beteiligte: Muehlematter, Urs J.; Rupp, Niels J.; Mueller, Julian; Eberli, Daniel; Burger, Irene A.
  • Erschienen: Ovid Technologies (Wolters Kluwer Health), 2018
  • Erschienen in: Clinical Nuclear Medicine
  • Sprache: Englisch
  • DOI: 10.1097/rlu.0000000000002143
  • ISSN: 1536-0229; 0363-9762
  • Schlagwörter: Radiology, Nuclear Medicine and imaging ; General Medicine
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  • Beschreibung: <jats:title>Abstract</jats:title> <jats:p>Multiparametric MRI incorporating T2-weighted, diffusion-weighted, and dynamic contrast material–enhanced sequences is currently used for detection and localization of clinically important prostate cancer (PCa). The <jats:sup>68</jats:sup>Ga-labeled PET tracer targeting the prostate-specific membrane antigen (PSMA, <jats:sup>68</jats:sup>Ga-PSMA-11) is a promising diagnostic approach for staging and restating PCa. Recent studies suggest that <jats:sup>68</jats:sup>Ga-PSMA could also be used for primary PCa detection and localization. We report a case of a <jats:sup>68</jats:sup>Ga-PSMA PET/MR-positive lesion of the peripheral zone in a 73-year-old man with a negative preceding multiparametric MRI. Radical prostatectomy and subsequent histopathologic examination confirmed a Gleason 4 + 4 PCa.</jats:p>