• Medientyp: E-Artikel
  • Titel: 68Ga-Oxine–Labeled Erythrocytes as a New PET Tracer for the Localization of Gastrointestinal Bleeding
  • Beteiligte: Leder, Theresa; Kühnel, Christian; Gröber, Sebastian; Drescher, Robert; Freesmeyer, Martin
  • Erschienen: Ovid Technologies (Wolters Kluwer Health), 2024
  • Erschienen in: Clinical Nuclear Medicine
  • Sprache: Englisch
  • DOI: 10.1097/rlu.0000000000005021
  • ISSN: 1536-0229; 0363-9762
  • Schlagwörter: Radiology, Nuclear Medicine and imaging ; General Medicine
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  • Beschreibung: <jats:title>Abstract</jats:title> <jats:p>A 69-year-old man presented with recurring drops in hemoglobin levels and suspected gastrointestinal bleeding. Endoscopy did not show a site of bleeding so further examinations became necessary. Scintigraphy and SPECT/CT with <jats:sup>99m</jats:sup>TcO<jats:sub>4</jats:sub> <jats:sup>−</jats:sup>–labeled red blood cells were performed without evidence of a hemorrhage. Based on an established protocol for splenic PET/CT, autologous erythrocytes can be labeled with <jats:sup>68</jats:sup>Ga-oxine and used as a tracer for the localization of active bleeding sites. In the patient, PET/CT with <jats:sup>68</jats:sup>Ga-oxine–labeled undamaged erythrocytes was performed successfully and revealed a hemorrhage of the gastric corpus that was confirmed and treated by endoscopy.</jats:p>