Beschreibung:
<jats:p>Pancreatic necrosis infection (PNI) accounts for about 20–40 % of severe acute pancreatitis. PNI caused by anaerobic bacteria is unusual but when they present, <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.3991" xlink:type="simple">Clostridium perfringens</jats:ext-link>
</jats:named-content>
</jats:italic> is the microorganism most commonly involved. We present a 60-year-old patient with a previous history of SARS-CoV-2, diagnosed with acute pancreatitis. During the hospitalisation he developed <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.3991" xlink:type="simple">Clostridium perfringens</jats:ext-link>
</jats:named-content>
</jats:italic> bacteraemia. A CT-scan showed pancreatic gas gangrene and a surgical necrosectomy was performed. <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.3991" xlink:type="simple">Clostridium perfringens</jats:ext-link>
</jats:named-content>
</jats:italic> was isolated in cultures of the pancreatic tissue and collections. The patient’s clinical status improved after surgery and the appropriate medical therapy. He was discharged 76 days after admission. Nowadays, the ‘step-up approach’ is an accepted therapeutic tool in treatment of pancreatic necrosis and peripancreatic fluid collections. However, most authors suggest that <jats:italic>Clostridum perfringens</jats:italic> infection requires a more aggressive approach due to the high mortality associated to clostridial infection.</jats:p>