• Medientyp: E-Artikel
  • Titel: A new essential gene located on Saccharomyces cerevisiae chromosome IX
  • Beteiligte: Kurlandzka, Anna; Rytka, Joanna; Gromadka, Robert; Murawski, Marcin
  • Erschienen: Wiley, 1995
  • Erschienen in: Yeast, 11 (1995) 9, Seite 885-890
  • Sprache: Englisch
  • DOI: 10.1002/yea.320110910
  • ISSN: 0749-503X; 1097-0061
  • Schlagwörter: Genetics ; Applied Microbiology and Biotechnology ; Biochemistry ; Bioengineering ; Biotechnology
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>A new 1150 amino acids long open reading frame (ORF), coding for an essential protein of unknown function was found <jats:italic>Saccharomyces cerevisiae</jats:italic> by sequencing 3754 bp of geonomic DNA. The clone was isolated in a search for a fatty acid‐binding protein (FABP) and was localized on chromosome IX. The ORF bears no homology to FABP, but it shows weak similarity to <jats:italic>Plasmodium vivax</jats:italic> reticulocyte binding protein 1 and to aggregation‐specific adenylate cyclase from <jats:italic>Dictyostelium discoideum</jats:italic>. The new gene is constitutively transcribed regardless of the carbon source used. The nucleotide sequence reported in this paper has been deposited in GenBank (Accession Number U17918).</jats:p>