Erschienen in:Annals of Clinical and Translational Neurology
Sprache:
Englisch
DOI:
10.1002/acn3.51877
ISSN:
2328-9503
Entstehung:
Anmerkungen:
Beschreibung:
<jats:title>Abstract</jats:title><jats:p>Experimental and neuroimaging studies suggest an influence of the time of day on acute infarct growth, but whether this could inform patient selection for acute treatments is uncertain. In a multicenter cohort of 9357 stroke patients undergoing endovascular treatment, morning treatment (05:00–10:59) was associated with lowest 90‐day mRS scores (adjusted odds ratio, 1.27 [95% CI, 1.08–1.47]; <jats:italic>p</jats:italic> = 0.004). The association between successful recanalization and outcome was stronger in morning compared to evening‐treated patients (<jats:italic>p</jats:italic><jats:sub>ia</jats:sub> = 0.046) with treatment benefit persisting until 24 h for morning‐treated compared to 11.5 h for evening‐treated patients suggesting that the time of day might inform patient selection for EVT.</jats:p>