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Medientyp:
E-Artikel
Titel:
Profiles of lifestyle health behaviors and cognitive decline in older adults
Beteiligte:
Halloway, Shannon;
Wagner, Maude;
Tangney, Christy;
Lange‐Maia, Brittney S.;
Bennett, David A.;
Arvanitakis, Zoe;
Schoeny, Michael E.
Erschienen:
Wiley, 2024
Erschienen in:
Alzheimer's & Dementia, 20 (2024) 1, Seite 472-482
Sprache:
Englisch
DOI:
10.1002/alz.13459
ISSN:
1552-5260;
1552-5279
Entstehung:
Anmerkungen:
Beschreibung:
AbstractINTRODUCTIONWe aimed to identify profiles of modifiable, late‐life lifestyle health behaviors related to subsequent maintenance of cognition and explore sociodemographics and health characteristics as effect modifiers.METHODSAnalyses used data from 715 older adults without baseline dementia from the Rush Memory and Aging Project and with lifestyle health behaviors (physical activity, cognitive activity, healthy diet, social activity) at baseline and ≥ 2 annual assessments of cognition. We used latent profile analysis to group participants based on behavior patterns and assessed change in cognition by group.RESULTSThree latent profiles were identified: high (n = 183), moderate (n = 441), and low (n = 91) engagement in health behaviors. Compared to high engagement, the moderate (mean difference [MD] = ‐0.02, 95% CI = [‐0.03;‐0.0002], p = 0.048) and low (MD = ‐0.06, 95% CI = [‐0.08;‐0.03], p < 0.0001) groups had faster annual rates of decline in global cognition, with no significant effects modifiers (vascular risk factors, apolipoprotein E [APOE] ε4, motor function).DISCUSSIONAvoiding low levels of lifestyle health behaviors may help maintain cognition.HighlightsLatent profile analysis (LPA) captures lifestyle health behaviors associated with cognitive function.Such behavior include physical activity, cognitive activity, healthy diet, social activity.We used LPA to examine associations of behaviors and cognitive function over time.Older adults with low lifestyle health behaviors showed more rapid decline.To a lesser degree, so did those with moderate lifestyle health behaviors.Vascular conditions and risks, APOEε4, or motor function did not modify the effect.