• Medientyp: E-Artikel
  • Titel: FLP‐Catalyzed Transfer Hydrogenation of Silyl Enol Ethers
  • Beteiligte: Khan, Imtiaz; Reed‐Berendt, Benjamin G.; Melen, Rebecca L.; Morrill, Louis C.
  • Erschienen: Wiley, 2018
  • Erschienen in: Angewandte Chemie, 130 (2018) 38, Seite 12536-12539
  • Sprache: Englisch
  • DOI: 10.1002/ange.201808800
  • ISSN: 0044-8249; 1521-3757
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: AbstractHerein we report the first catalytic transfer hydrogenation of silyl enol ethers. This metal free approach employs tris(pentafluorophenyl)borane and 2,2,6,6‐tetramethylpiperidine (TMP) as a commercially available FLP catalyst system and naturally occurring γ‐terpinene as a dihydrogen surrogate. A variety of silyl enol ethers undergo efficient hydrogenation, with the reduced products isolated in excellent yields (29 examples, 82 % average yield).