• Medientyp: E-Artikel
  • Titel: Cellular Immune Recognition and the Biological Role of Major Transplantation Antigens (Nobel Lecture)
  • Beteiligte: Zinkernagel, Rolf M.
  • Erschienen: Wiley, 1997
  • Erschienen in: Angewandte Chemie International Edition in English
  • Sprache: Englisch
  • DOI: 10.1002/anie.199719381
  • ISSN: 0570-0833
  • Schlagwörter: Psychiatry and Mental health
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  • Beschreibung: <jats:p><jats:bold>In the complex balance between virus and host</jats:bold> the T cells and the properties of the virus play an important role. The unexpected discovery of the MHC‐restricted T cell recognition (MHC = major histocompatibility complex) prompted many important investigations. Which have led to a detailed understanding on a molecular level of T cell recognition of virus‐infected target cells. As a result of these findings the immunological specificity as well as the immunological memory, and above all, pathogenesis of infectionus diseases and of autoimmunity can be better understood.</jats:p>