• Medientyp: E-Artikel
  • Titel: Sigillin A, a Unique Polychlorinated Arthropod Deterrent from the Snow Flea Ceratophysella sigillata
  • Beteiligte: Schmidt, Witali; Schulze, Thies M.; Brasse, Gregor; Nagrodzka, Edyta; Maczka, Michael; Zettel, Jürg; Jones, Peter G.; Grunenberg, Jörg; Hilker, Monika; Trauer‐Kizilelma, Ute; Braun, Ute; Schulz, Stefan
  • Erschienen: Wiley, 2015
  • Erschienen in: Angewandte Chemie International Edition, 54 (2015) 26, Seite 7698-7702
  • Sprache: Englisch
  • DOI: 10.1002/anie.201501719
  • ISSN: 1433-7851; 1521-3773
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  • Beschreibung: AbstractThe snow flea Ceratophysella sigillata, a winter‐active species of springtail, produces unique polychlorinated octahydroisocoumarins to repel predators. The structure of the major compound, sigillin A, was elucidated through isolation, spectroscopic analysis, and X‐ray crystallography. Sigillin A showed high repellent activity in a bioassay with predatory ants. A promising approach for the total synthesis of members of this new class of natural compounds was also developed.