Poordad, Fred;
Lawitz, Eric;
Gutierrez, Julio A.;
Guerrero, Juan;
Speeg, Kermit;
Swenson, Eugene S.
An HCV‐positive recipient of an HCV‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin
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Medientyp:
E-Artikel
Titel:
An HCV‐positive recipient of an HCV‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin
Beteiligte:
Poordad, Fred;
Lawitz, Eric;
Gutierrez, Julio A.;
Guerrero, Juan;
Speeg, Kermit;
Swenson, Eugene S.
Beschreibung:
<jats:title>Key Clinical Message</jats:title><jats:p>This case suggests that initiation of <jats:styled-content style="fixed-case">HCV</jats:styled-content> therapy immediately after liver transplantation with well‐tolerated, all‐oral regimens may achieve a virologic cure in <jats:styled-content style="fixed-case">HCV</jats:styled-content>‐positive recipients, thus preventing post‐transplant <jats:styled-content style="fixed-case">HCV</jats:styled-content> recurrence and associated disease progression. This strategy may broaden utilization of <jats:styled-content style="fixed-case">HCV</jats:styled-content>‐positive donor livers, potentially including <jats:styled-content style="fixed-case">HCV</jats:styled-content>‐negative transplant recipients.</jats:p>