Beschreibung:
<jats:p>In the present study the esterification of the OH groups of resveratrol, caffeic acid, ferulic acid, and <jats:italic>β</jats:italic>‐sitosterol with an antioxidant polyconjugated fatty acid, (2<jats:italic>E</jats:italic>,4<jats:italic>E</jats:italic>,6<jats:italic>E</jats:italic>)‐octa‐2,4,6‐trienoic acid, was achieved. As the selective esterification of OH groups of natural compounds can affect their biological activity, a selective esterification of resveratrol and caffeic acid was performed by an enzymatic approach. The new resulting compounds were characterized spectroscopically (FT‐IR, NMR mono, and bidimensional techniques); when necessary the experimental data were integrated by quantum chemical calculations. The antioxidant, anti‐inflammatory and proliferative activity was evaluated. The good results encourage the use of these molecules as antioxidant and/or anti‐inflammatory agents in dermocosmetic application.</jats:p>