Erschienen in:
Chemistry – A European Journal, 21 (2015) 28, Seite 10014-10018
Sprache:
Englisch
DOI:
10.1002/chem.201501553
ISSN:
0947-6539;
1521-3765
Entstehung:
Anmerkungen:
Beschreibung:
AbstractThe direct, nucleophilic imidation of acetanilide derivatives has been performed under mild, iodine(III)‐mediated or ‐catalyzed conditions, employing lithium triflimide as the nitrogen source. The reaction exhibits exclusive regioselectivity for the para position and shows a good tolerance for varied functional groups at both the ortho or meta positions. Preliminary mechanistic data suggest that the LiNTf2 reagent plays a key role in the reactivity.