• Medientyp: E-Artikel
  • Titel: Convenient Synthesis of 11‐Substituted 11H‐Indolo[3,2‐c]quinolines by Sequential Chemoselective Suzuki Reaction/Double C–N Coupling
  • Beteiligte: Pham, Ngo Nghia; Janke, Sophie; Salman, Ghazwan Ali; Dang, Tuan Thanh; Le, Thanh Son; Spannenberg, Anke; Ehlers, Peter; Langer, Peter
  • Erschienen: Wiley, 2017
  • Erschienen in: European Journal of Organic Chemistry, 2017 (2017) 37, Seite 5554-5565
  • Sprache: Englisch
  • DOI: 10.1002/ejoc.201700913
  • ISSN: 1434-193X; 1099-0690
  • Schlagwörter: Organic Chemistry ; Physical and Theoretical Chemistry
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  • Beschreibung: A pathway to access 11‐substituted 11H‐indolo[3,2‐c]quinolines is described. The protocol features a chemoselective Suzuki reaction of o‐dihaloquinolines with o‐bromophenylboronic acid, followed by double C–N coupling with primary amines. The molecular structure of a representative product is exemplified, and demonstrates well‐defined π‐stacking interactions in the molecular network.