• Medientyp: E-Artikel
  • Titel: Evidence for a new lymphocyte‐stimulating determinant (Lsd) detected by alloreactive T cell lines
  • Beteiligte: Opalka, Bertram; Kölsch, Eckehart
  • Erschienen: Wiley, 1983
  • Erschienen in: European Journal of Immunology
  • Sprache: Englisch
  • DOI: 10.1002/eji.1830130107
  • ISSN: 0014-2980; 1521-4141
  • Schlagwörter: Immunology ; Immunology and Allergy
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>Three alloreactive T cell clones are described which reveal a new lymphocytestimulating determinant (Lsd) controlled by a gene on chromosome 1 of the mouse but different from and possibly centromeric to Mls. Two clones were originally isolated as anti‐H‐2<jats:sup>b</jats:sup>‐specific and showed and retained cross‐reactivity to Lsd (clone OD3, BALB/c anti‐C57BL/6; clone KB37, B10.BR anti‐C57BL/10). The third clone (BD7, C57BL/6 anti‐CBA/J) was probably originally directed against Lsd. So far, Lsd is only characterized by stimulation of T cell proliferation, and its physiological function is not yet known.</jats:p>