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Medientyp:
E-Artikel
Titel:
Ultrasound‐guided resection for squamous cell carcinoma of the buccal mucosa: A feasibility study
Beteiligte:
Adriaansens, Carleen M. E. M.;
de Koning, Klijs J.;
de Bree, Remco;
Dankbaar, Jan Willem;
Breimer, Gerben E.;
van Es, Robert J. J.;
Noorlag, Rob
Erschienen:
Wiley, 2023
Erschienen in:
Head & Neck, 45 (2023) 3, Seite 647-657
Beschreibung:
<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Image‐guided surgery could help obtain clear (≥5.0 mm) resection margins. This feasibility study investigated ultrasound‐guided resection accuracy of buccal mucosa squamous cell carcinoma (BMSCC).</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>MRI and ultrasound measurements of tumor thickness were compared to histology in 13 BMSCC‐patients. Ultrasound measured margins (at five locations) on the specimen were compared to the corresponding histological margins.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Accuracy of in‐ and ex‐vivo ultrasound (mean deviation from histology: 1.6 mm) for measuring tumor thickness was comparable to MRI (mean deviation from histology: 2.6 mm). The sensitivity to detect <5mm margins using ex‐vivo ultrasound was low (48%). If an ex‐vivo ultrasound cutoff of ≥7.5 mm would be used, the sensitivity would increase to 86%.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Ultrasound‐guided resection of BMSCC's is feasible. In‐ and ex‐vivo ultrasound measure tumor thickness in BMSCC accurately. We recommend ≥7.5 mm resection margins on ex‐vivo ultrasound to obtain histological clear margins. Additional research is required to establish the effect of 7.5 mm ultrasound cutoff.</jats:p></jats:sec>