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Medientyp: E-Artikel Titel: Trichosporon: another yeast‐like organism responsible for immune reconstitution inflammatory syndrome in patients with hematological malignancy Beteiligte: Alby‐Laurent, Fanny; Dollfus, Catherine; Ait‐Oufella, Hafid; Rambaud, Jerome; Legrand, Ollivier; Tabone, Marie‐Dominique; Hennequin, Christophe Erschienen: Wiley, 2017 Erschienen in: Hematological Oncology, 35 (2017) 4, Seite 900-904 Sprache: Englisch DOI: 10.1002/hon.2309 ISSN: 0278-0232; 1099-1069 Schlagwörter: Cancer Research ; Oncology ; Hematology ; General Medicine Entstehung: Anmerkungen: Beschreibung: AbstractTrichosporon has recently emerged as a life‐threatening opportunistic fungal pathogen, notably in patients with hematological malignancy. Fungemia, sometimes associated with cutaneous lesions and/or pneumonitis, is the major clinical form. Here, we report two cases of patients suffering from acute leukaemia who developed hepatic and/or splenic lesions apart from Trichosporon positive blood cultures. The appearance of hepatic and splenic lesions following the recovery from neutropenia is highly suggestive of a chronic disseminated infection, now considered as an immune reconstitution inflammatory syndrome. Treatment with corticosteroid therapy led to clinical improvement in both cases. Copyright © 2016 John Wiley & Sons, Ltd.