• Medientyp: E-Artikel
  • Titel: Der Stoffwechsel von Verbindungen mit Dreifachbindung V. Der Abbau von Diincarbonsäuren und Kohlenwasserstoffen in vivo
  • Beteiligte: Bernhard, Karl; Kaempf, Ekkehard
  • Erschienen: Wiley, 1970
  • Erschienen in: Helvetica Chimica Acta
  • Sprache: Englisch
  • DOI: 10.1002/hlca.19700530731
  • ISSN: 0018-019X; 1522-2675
  • Schlagwörter: Inorganic Chemistry ; Organic Chemistry ; Physical and Theoretical Chemistry ; Drug Discovery ; Biochemistry ; Catalysis
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>10,12‐Heneicosadiynoic acid (I), 5,7‐hexadecadiynoic acid (IV), and 10,12‐docosadiynedioic acid (VI) were fed to rats. As metabolites 4,6‐undecadiynedioic acid (II), 5,7‐dodecadiynedioic acid (V), and 4,6‐decadiynedioic acid (VII) respectively were isolated from the urine. 10,12‐Heptadecadiynoic acid (III) also yielded metabolite II. Furthermore 9,11‐eicosadiyne (X) and for comparison purposes eicosane (XI), hexadecanedioic acid (VIII), and docosanedioic acid (IX) were fed. X and XI were incorporated into depot fat and liver lipids to a cetain degree. The diynes I, II, IV, and X are new compounds.</jats:p>