• Medientyp: E-Artikel
  • Titel: Thiazolidine‐4‐ones from Thiocarbohydrazides
  • Beteiligte: Hassan, Alaa A.; Makhlouf, Maysa M.
  • Erschienen: Wiley, 2018
  • Erschienen in: Journal of Heterocyclic Chemistry
  • Sprache: Englisch
  • DOI: 10.1002/jhet.3315
  • ISSN: 0022-152X; 1943-5193
  • Schlagwörter: Organic Chemistry
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p>Several methods for the preparation of thiazolidin‐4‐ones from thiocarbohydrazides over the last 15 years are highlighted. Thiosemicarbazides, thiocarbohydrazides, thioamides, and hydrazinecarbothioamides as well as thioureas were used to obtain different substituted thiazolidinones under reaction conditions. Thiazolidinones can be synthesized either by a one‐pot three‐component condensation or a two‐step process. Also, the mechanism of formation, regioselectivity issues, and biological activities of different thiazolidinones were discussed.</jats:p>