Beschreibung:
<jats:title>ABSTRACT</jats:title><jats:p><jats:italic>Introduction</jats:italic>: Fibromyalgia (FM) is a chronic syndrome characterized by widespread pain often accompanied by other symptoms suggestive of neuropathic pain. We evaluated patients for small fiber neuropathy (SFN) who were referred for fibromyalgia (FM). <jats:italic>Methods</jats:italic>: We studied 20 consecutive subjects with primary FM. Patients underwent neurological examination, nerve conduction studies, and skin biopsies from distal leg and thigh. <jats:italic>Results</jats:italic>: Electrodiagnostic studies were normal in all patients. SFN was diagnosed in 6 patients by reduced epidermal nerve fiber density. These patients also showed abnormalities of both adrenergic and cholinergic fibers. <jats:italic>Conclusions</jats:italic>: A subset of FM subjects have SFN, which may contribute to their sensory and autonomic symptoms. Skin biopsy should be considered in the diagnostic work‐up of FM. <jats:italic>Muscle Nerve</jats:italic> <jats:bold>49</jats:bold>: 757–759, 2014</jats:p>